A group of patients that share a common trait or condition. Patient cohorts are used to build comprehensive biomedical databases or biobanks which include clinical and molecular data from patients with diseases to provide molecular insights to drive research and drug discovery.
Patient subgroup / population**
A specific group of individuals with common characteristics e.g., specific disease drivers, ethnicity, age or risk factors.
Sequencing¶
Techniques to determine the sequence / primary structure of a biological polymer. For example, DNA sequencing aims to determine the exact order of the four nucleotide bases of a strand of DNA of an individual patient.
Single nucleotide polymorphism (SNP)¶
A DNA variation caused by a single nucleotide (base pair) at a specific position in the genome.
Targeted therapy / treatment*
Specifically designed or selected to interact / interfere with particular molecular targets.